The research in our lab is centered around understanding how the mechanisms that evolved to regulate body temperature can be repurposed to combat obesity and metabolic diseases in humans. Brown adipose tissue (BAT) is responsible for regulating body temperature through adaptive thermogenesis. Harnessing the potential of thermogenic adipocytes to enhance energy expenditure offers an effective strategy against obesity and metabolic disorders such as type 2 diabetes, cardiovascular diseases, and many cancers.

Our long-term vision is to pioneer strategies for rejuvenating thermogenic fat by preventing or reversing its age- and obesity-induced decline.